September 24, 20241 yr Active Members I attended a medical lecture regarding the RSV vaccine 2 weeks ago, and it wasn't extremely encouraging. There is some data potential recipients should know before agreeing to the vaccine (we're talking about the 60+ group, not for infants or pregnant mothers, which is a different kettle of fish). The absolute risk reduction to prevent one lower respiratory (lung) infection in adults is 0.26% (need to immunize 385 to prevent one serious infection), and the absolute risk reduction to prevent one hospitalization is 0.13% (need to immunize 770 to prevent one hospitalization). There was no significant difference in death. Also, muscle aches and flu-like symptoms were common, with risks of 44% and 51.6%. That being said, serious adverse reactions were rare, although about 1 in 2000 got Guillain–Barré syndrome, a fairly devastating neurological complication, and none of the placebo did (too rare to be called a significant difference). I'm not encouraging or discouraging getting it, but I think one should be aware of what the potential benefits and risks are before consenting. Also, the vaccine only appears to last one season. https://meridian.allenpress.com/jcphp/article/70/4/27/498435/Evidence-Based-Appraisal-of-Respiratory-Syncytial
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