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Prostate cancer trial: Radiotherapy doses can be cut safely

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From the BBC

By Fergus Walsh
Medical editor

Men undergoing treatment for prostate cancer could be safely given far less radiotherapy, a major trial has found.

Doses can be cut by three-quarters meaning five higher doses is enough, instead of the 20 or so given now.

The international trial involved nearly 900 men with medium-risk prostate cancer that had not spread.

Lead researcher Prof Nicholas van As from the Royal Marsden Hospital said the results were "outstanding" and "fantastic" for patients.

Prostate Cancer UK said the finding had the potential to save time and money for the NHS, while still giving men the best outcomes.

It means thousands of men could be given larger doses of radiotherapy - also known as multi-beam radiotherapy - at each hospital visit, but less overall.

The study found that after five years, 96% of the men who received five doses of the multi-beam radiotherapy were cancer-free, compared to 95% who received at least 20 doses of standard radiotherapy.

Side effects, such as needing to pass urine more often, were low in both groups.

The top-line results of the PACE-B trial will be released at the American Society for Therapeutic Radiation and Oncology (Astro) conference in San Diego.

Prof van As said he expected the results to lead to "enormous change" in the way radiotherapy was delivered.

https://www.bbc.com/news/health-66946336

 

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I've had prostate cancer and chose what I thought was the best option:  remove it once and for all.  I was fortunate that the cancer was encapsulated in the prostate and had not metastasized and no further treatment was necessary.  My brother had and continues to have prostate cancer, opted for radiation and now the cancer has spread and is reeking havoc with him.  There's no one right answer that applies to all who have this cancer.  I consider myself lucky, though my sex life is substantially reduced ... but I'm alive.  I'll take the sex loss, gladly.

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