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VACCINATED

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On 4/4/2021 at 8:02 PM, faranglaw said:

So I’m here in Vancouver, born in 1950 and currently the province is only making appointments for people born 1949 and before

Sounds like the wait is over for you. Those born in 1950 (and earlier) can now book their appointments on line

Good luck!

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Got the Johnson & Johnson vaccine about 18 hours ago. It is a single dose vaccine with an efficacy rate of about 70% compared to 95% for Pfizer and Moderna. It was a quick and easy process. They asked about any allergies you may have, and how you reacted to them. I had to wait for 15 minutes after the shot before I could leave. 

I didn't experience any pain at the injection spot, and so far my only reaction is a mild body ache like when you're sick. Most people I know got the Moderna vaccine as it was available sooner. Most of them complained of sore arms and more severe flu like symptoms such as chills, headaches and body aches. However, symptoms usually went away after a day at most, after taking pain killers and getting bed rest. 

Getting vaccinated makes me feel better because I've noticed a sense of complacency about masks and social distancing where I live, especially outdoors. I have co-workers and family who are immuno-compromised so I feel like I'm doing my part to help keep them safe.

 

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On 4/9/2021 at 10:07 PM, fedssocr said:

Got the J&J/Jansen one shot vaccine this morning. Very well organized vaccination center operated by my county. Really feeling the effects now 14 hours later. Body aches, slight fever, fatigue. I see that as a good sign. 

I had the J&J vaccine as well. I felt fine the first day, but then had an all-day headache the next.

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15 hours ago, Half-vaccinated said:

I'm off to my next shot in early May.  I personally do not believe they are necessary. 

You are, of course, entitled to your opinion. In my opinion it is necessary and I encourage everyone to stick to the CDC guidelines when it comes to getting the 2nd shot. 

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It puzzles me at this point why nomenclature such as the vaccine and the shot(s) is still utilized. It’s as if one goes to the fast-food restaurant and has the hamburger ... when in a rush and a pinch it is a good option to go to a fast-food restaurant and have a hamburger. 

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I had the Moderna.   My arm was sore for two days after the first one.  I took two Tylenol tabs.  After the second one, I felt listless and faint for a few hours along with having a slight pain the arm.  To date, I feel fine and am still utilizing all protocols. 

Next month I fly to Kansas City to be with my mother on her 101th birthday.  Because Southwest has funky schedules now as well as booking the middle seat, I chose to fly American first class and hope no one sits next to me.

Continue to wear your masks, social distance, and wash those hands.

[I will see an escort and/or masseur only if he has been vaccinated and can show proof of it.  I have my card that shows that I've been stuck.]

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On 2/1/2021 at 4:49 PM, Riobard said:

I don’t mean to interfere but I would not hold my tongue for a personal close relation, so   ...

Thailand has committed to the Sinovac vaccine but the efficacy data are poor. It is launching in Brazil which was a main research location and was given emergency authorization there mainly due to political wrangling and desperation. 

You might consider holding out for the AstraZeneca vaccine that is also planned by Thailand. The low case incidence may allow the luxury of waiting a bit. The volume of doses is much higher than the SinoVac contract. 

There is a little Phase 1 vaccine research study apparently starting up at Chula U. It is mRNA model like the Pfizer/BioNTech and Moderna models. Everybody gets the vaccine; it is not placebo-controlled at this stage. 

I am returning to this basically because I had questioned the value of CoronaVac. Not that I should be considered an influencer either way, but I should point out that this vaccine now seems to be proving itself reasonably well in overall real-world effectiveness, 67%, in Chile and is acquiring much acceptance particularly in Brazil. Also large reductions in hospitalization and death.

The good PR reduces hesitancy there and that can compensate somewhat for lesser efficacy relative to some of the other vaccines. It also appears to come with minimal side effects / adverse events.

I did not want to trash-talk it a while ago and then fail to report more recent news about it as well as my increased optimism about this Sinovac product.

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Our gov just released a statement regarding infection occured after vaccination amings hospital workers. 9 were infected with less severe covid after 2 weeks receiving the vaccine. Much higher number were reported for less than 2 week of 2nd dose (39) and after receiving 1st dose (142) which is expected. Basically vaccinated hospital workers where SOP were observed very strictly, but of course exposed to the virus at a higher level as well, still can be infected, with less severe symptoms. All hospital workers are taking the 2 dose pfizer-moderna vaccine, cominarty. Our DG health ended the announcement with a call for everyone, vaccinated or not, to be vigilant and observed SOP until we reached herd immunity. 

https://www.straitstimes.com/asia/se-asia/healthcare-workers-in-malaysia-infected-after-covid-19-vaccination-reported-less-severe

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1 hour ago, spoon said:

Our gov just released a statement regarding infection occured after vaccination amings hospital workers. 9 were infected with less severe covid after 2 weeks receiving the vaccine. Much higher number were reported for less than 2 week of 2nd dose (39) and after receiving 1st dose (142) which is expected. Basically vaccinated hospital workers where SOP were observed very strictly, but of course exposed to the virus at a higher level as well, still can be infected, with less severe symptoms. All hospital workers are taking the 2 dose pfizer-moderna vaccine, cominarty. Our DG health ended the announcement with a call for everyone, vaccinated or not, to be vigilant and observed SOP until we reached herd immunity. 

https://www.straitstimes.com/asia/se-asia/healthcare-workers-in-malaysia-infected-after-covid-19-vaccination-reported-less-severe

Based on the pic below, the observation was from a total of 426 workers. FB_IMG_1618642364490.jpg.f08a0702115dfc3b4035591d43168591.jpg

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@spoon, vaccinated, not vaccinated, post-vaxx duration aside, 43% CoV incidence among HCWs is 269X background cumulative incidence for Malaysia’s genpop (.16%) over the same 40 days. The higher rates in HCWs in other studies are usually up to 2-fold, not well over 200-fold. That would cripple any health care system.

The report and illustration do not make sense. It seems impossible to me unless the HCWs had volunteered to be exposed to almost inevitable infection. Was it a ‘challenge’ study? The wording says “were infected” ... semantically that could mean they were planfully exposed as opposed to ‘they acquired infection randomly’. 

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Im not sure who among the hcw is the 426, my guess would be these are those who are directly handling covid patient thus high exposure to the virus themselves. And i also think there are some relaxation of the strict PPE after vaccination?, Again, not much is being discusses as this was not a peer review technical paper but just an effort by MOH to show the public why they cant allow a more relax restriction fot vaccinated person. Total incident was from the first dose until 2 weeks after vaccination. At full immunity, it was only 9, which does shows significant reduction of infection among them. 

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16 minutes ago, spoon said:

Im not sure who among the hcw is the 426, my guess would be these are those who are directly handling covid patient thus high exposure to the virus themselves. And i also think there are some relaxation of the strict PPE after vaccination?, Again, not much is being discusses as this was not a peer review technical paper but just an effort by MOH to show the public why they cant allow a more relax restriction fot vaccinated person. Total incident was from the first dose until 2 weeks after vaccination. At full immunity, it was only 9, which does shows significant reduction of infection among them. 

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1 hour ago, spoon said:

Im not sure who among the hcw is the 426, my guess would be these are those who are directly handling covid patient thus high exposure to the virus themselves. And i also think there are some relaxation of the strict PPE after vaccination?, Again, not much is being discusses as this was not a peer review technical paper but just an effort by MOH to show the public why they cant allow a more relax restriction fot vaccinated person. Total incident was from the first dose until 2 weeks after vaccination. At full immunity, it was only 9, which does shows significant reduction of infection among them. 

[Sorry, the system would not allow my script after I quoted you in the previous field.]

The rate (proportion) of infection among the fully vaccinated HCWs is 2.1% over a brief time period. The rate within the vaccination assignment arm in Pfizer\BNT over a longer time period is .043%.

Vaccination among these Malaysian HCWs did not work well because they were 48 times as likely to acquire CoV compared to those vaccinated in the efficacy trial and were 13 times as likely to acquire CoV as the (mostly) unvaccinated general population.

Vaccinated HCWs in the Brazilian CoronaVac efficacy trial also had a similar incidence, close to 2%. However, that was consistent with the unvaccinated general pop. Yet it suggests that in the real world Malaysia HCW setting the mRNA products were no better than CoronaVac. Though no placebo control or non-vaxx’d HCW group to truly assess the effectiveness in the Malaysia study. 

Perhaps the Malaysian HCWs were in a high concentration of incidence. They really take a hit. How many people would want to risk a 1/50 chance of going to work and getting infected shortly following the recommended vaxx dose cycle?

CDC just reported an estimated .009% breakthrough infections among those fully vaccinated, over 2,000 times these Malaysian HCWs. 

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I do believe that there is a mix of lax in SOP adherence amongs vaccinated HCW and high exposure to virus. We do have relatively high amount of cases in some hospitals in big cities, and several strains that were a big concern now is already here (south african variant). The main point is still valid, vaccinated or not, we still need to be vigilant and observe social distancing and mask wearing. 

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12 hours ago, Riobard said:

@spoon

The report and illustration do not make sense. It seems impossible to me unless the HCWs had volunteered to be exposed to almost inevitable infection. Was it a ‘challenge’ study? The wording says “were infected” ... semantically that could mean they were planfully exposed as opposed to ‘they acquired infection randomly’. 

Ok i believe i understand the histogram now. 426 is the total of HCW infected. 140 of them infected after receiving first dose, 31 after second dose, 9 after 2 weeks of 2nd dose. The rest are infected without receiving their first dose yet. The total of vaccinated HCW daily are unknown but i recalled that registered Frontliner were in the region of 300k-400k. So 426 total infected out of total 300k plus (0.00014 max)

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11 hours ago, spoon said:

Ok i believe i understand the histogram now. 426 is the total of HCW infected. 140 of them infected after receiving first dose, 31 after second dose, 9 after 2 weeks of 2nd dose. The rest are infected without receiving their first dose yet. The total of vaccinated HCW daily are unknown but i recalled that registered Frontliner were in the region of 300k-400k. So 426 total infected out of total 300k plus (0.00014 max)

But this Tweet from what appears to be an official local epi Twitter site, @spoon ... then they posted a USA example of breakthrough infection. Is it meant to be sarcastic? If so, why would they add the part about preventing severity and death? 

Maybe the doctor did not present the actual HCW Ndenominator because it was not precisely known. 

On the doctor’s Facebook page (Noor Hisham Abdullah) one English comment on the low incidence after all, but it follows some Malay comments so I cannot really figure out that thread.

BTW, in either case the numerator is 182, not 426.

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C1448E81-8643-412D-9E16-D30A7E84679C.jpeg

AEC86F4C-F24C-4ECE-8AE3-1F6AC869F5B9.jpeg

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Sorry, @spoon, the confusion is not resolved. Another article says the 438,000 vaccinated is in total pop, not specifically HCWs. Also, the guy put 244 non-infected into the calculation so the denominator has to be 426, not 438,000 ... this puts the vaxx’d HCWs at 2.1% infected at the point immunity should have been conferred, suggesting it was a small cohort all vaccinated on the first of the 40 days and followed for CoV status. There is no way 438,000 could have been simultaneously vaccinated on March 7th.

So this now means a contradiction in the screenshot above from The Star. He said the fully properly vaccinated HCWs had negligible incidence. There is now a paywall so I cannot return to it. 

My worry is that he was so intent on underscoring the importance of additional vigilance following the period of vaxx up to sufficient protective immunity that he royally messed up the data. 

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So I put this as a comment, one of hundreds made by others on this report, on the gov’t doctor’s FB:

The denominator is 426 vaccinated HCWs, not 430K+ HCWs in the nation of which some of the whole collective of HCWs received vaxx. 244 non-infected were included as it is a small cohort inoculated with 1st dose on the same day (presumably)?? This makes the CoV rate among the HCWs correctly vaccinated 2.1%, not 9+31 vaccinated out of 430K+, which would be negligible. What is totally confusing is that in the later days of the 40-day period the share of infections is high among those that had been fully vaccinated for at least 2weeks. The design needs to be clearly elaborated in order to interpret the pie chart and histogram. Does ‘none’ mean non-vaccinated or non-infected? If it means non-vaccinated, why were so many partially or even fully vaccinated HCWs infected relative to the non-inoculated? And that makes 9/142 = 4.9% of the fully vaxx’d HCWs infected.

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